Previously, we showed that the expression of ST3Gal IV in gastric carcinoma cells leads to SLex biosynthesis on both membrane-associated and secreted glycoproteins 12, 17 with a specific range of glycomic changes characterized mainly by the increased expression of α2-3 linked N‐acetylneuraminic acid (NeuAc) 17, 35. Here, ST3GAL4 is linked to gastric carcinoma.