The predicted target sites interactions among LncCCAT1, miR-148a/152 and DNMT1 3'-UTR are illustrated in Figure 4G. miR-148a/152 overexpression reduced DNMT1 protein levels, while miR-148a/152 knockdown increased DNMT1 protein levels in two breast cancer cell lines, in contrast to the effect of LncCCAT1 overexpression or knockdown on DNMT1 protein (Figure S3D, Figure 4H). Here, DNMT1 is linked to breast carcinoma.