Second, different combinations of ten genes (RTEL1, TERT, TERC, STN1, ATM, SP110, SEMA3E, TBX1, DNMT3B, CDCA7) related to the category “Combined immunodeficiencies with associated or syndromic features” were overrepresented in 11 neoplastic diseases/traits. Here, TBX1 is linked to severe combined immunodeficiency.