IL6 and systemic lupus erythematosus: An inference from our results is that anti-IL-6 antibodies or TLR7 antagonists may be ineffective, or only partially effective, in preventing lupus, and the failure of an anti-IL-6 monoclonal antibody to achieve its primary end goals in a phase 2 clinical trial for lupus (Wallace et al, 2017) is consistent with this notion.