IRAK4 and systemic lupus erythematosus: A different IRAK4 inhibitor (BMS-986126) has been shown to reduce the level of anti-dsDNA in the serum and to suppress kidney pathology in two other lupus-prone mouse lines (Murphy Roths Large/ lymphoproliferation (MRL/lpr) and New Zealand Black/White (NZB/W) mice) (Dudhgaonkar et al, 2017), but its efficacy in alleviating the pathology and inflammation of other organs was not reported.