These include polymorphisms in TNIP1, the gene encoding A20-binding inhibitor of NF-κB1 (ABIN1), which has been reported to predispose to SLE in many human populations (Gateva et al, 2009; Han et al, 2009; Nair et al, 2009; Adrianto et al, 2012; Gregersen et al, 2012; Shi et al, 2014). This evidence concerns the gene TNIP1 and systemic lupus erythematosus.