The expansion of the myeloid compartment was most pronounced in tumor tissue and identified as CD11b+Ly6CintLy6G+ PMN-MDSC and CD11b+Ly6ChiLy6G− M-MDSC, as well as CD11b+Ly6Clow/int F4/80+ macrophages, as major cell populations (Fig. 1c). The gene discussed is ITGAM; the disease is neoplasm.