To explore the clinical significance of these findings, we used the TCGA provisional data set for invasive breast carcinoma in cBioPortal to analyze if BMP-antagonists were co-expressed with either BMP2, BMP4, or BMP7. We found that many of the biopsies with a BMP amplification, also had an amplification of a gene encoding one of the BMP-antagonists (Fig. 2c). The gene discussed is BMP2; the disease is invasive breast carcinoma.