CRP rs1205 and rs876537 C > T variations were significantly correlated with hs-CRP, after adjusted for age, gender, BMI, TC, TG, HDL-C, LDL-C, smoking, drinking, T2DM and hypertension, the standard regression coefficients were 0.064 and 0.066, respectively, P < 0.001. This evidence concerns the gene CRP and type 2 diabetes mellitus.