CST3 and coronary artery disorder: With each index introduced per 1 SD increase, and adjustments for systolic blood pressure, smoking, cystatin C, albuminuria, Charlson comorbidity index, and a history of CHD, SPISE-IR estimated in all patients disclosed a significant HR of 1.20 (1.02–1.40; p = 0.03), with a similar magnitude of HR as the other three fasting indexes, and with similar values of LR test and Harrell’s C. However, SPISE-IR was the only significant index (p = 0.02), and with the highest HR of 1.53, among all four fasting indexes, when analyzing the highest quartile versus the lower three quartiles.