Nevertheless, 10 proteins (BAX, DERL2, DNAJA1, HSP90AA1, HSPA2, HSPA4, HSPA4L, HSPA5, LMNA, and STUB1) were also associated to infertility-related phenotypes in KO mouse models, comprising asthenozoospermia, azoospermia, arrest of spermatogenesis, abnormal spermatogenesis, abnormal Sertoli cells morphology, and others (Figure S3: Sperm UPR-related proteins). The gene discussed is HSPA5; the disease is Azoospermia.