With published data of RNA levels in PCa samples [86] retrieved from Geen Expression Omnibus (GEO Accession: GSE21032), the change fold expression of HMGB1 and HMGB2-interactome targets in PCa cell lines versus noncancerous cells was calculated, from which a heat map was constructed (Figure 5a). This evidence concerns the gene HMGB2 and posterior cortical atrophy.