To investigate the expression of PIWIL1 in human normal and cancerous tissues, we mined RNA-Seq data in The Cancer Genome Atlas (TCGA) and/or the Genotype-Tissue Expression (GTEx) databases, including 9736 tumoral (T) and 8587 non-tumoral (N) samples organized in 31 cohorts. Here, PIWIL1 is linked to cancer.