Interestingly, three astrocytic tumors harbored SMARCB1 hemizygous deletions, which have not been reported but are present in multiple pediatric high-grade glioma cohorts (Mackay et al., 2017: 6.7%, n = 834; Ijaz et al., 2019: 7.5%, n = 93) and may warrant further investigation. This evidence concerns the gene SMARCB1 and central nervous system cancer.