H3C3 and astrocytoma (excluding glioblastoma): Astrocytoma models comprised pleomorphic xanthroastrocytomas (PXA; n = 2), MYCN subtype (n = 2), glioblastomas (IDH-wild-type; n = 5), histone H3-wild-type diffuse intrinsic pontine glioma (DIPG; n = 2), and a histone H3-wild-type astrocytic tumor (n = 1).