Another eastern-population based retrospective study have comprehensively considered the expression of CEA, CA50, and CA724 to assess their clinical significances in predicting prognosis and built nomograms to predict the overall survival (OS) and disease-free survival (DFS) in CRC patients after radical resection, indicating the above tumor biomarkers have an important role in monitoring recurrence and metastasis [4]. The gene discussed is CEACAM5; the disease is colorectal carcinoma.