Regarding KEGG pathway functions associated with the feather follicles, significant differences were found in the following signaling pathways: calcium, PI3K-Akt, mTOR, cAMP, MAPK, Wnt, cGMP-PKG, Jak-STAT and adrenergic signaling in cardiomyocytes, melanogenesis, tyrosine metabolism, and melanoma. This evidence concerns the gene MTOR and melanoma.