Recently, LHPP is reported to play an essential role in inhibiting human HCC progression by regulating phosphatidylinositol‐3‐kinase/protein kinase B (PI3K/AKT) signaling pathway, and the loss of LHPP expression is also associated with reduced survival in HCC.9 Zheng et al17 also found that LHPP expression levels were markedly reduced in human cervical cancer tissue samples compared to the adjacent normal tissue. This evidence concerns the gene LHPP and hepatocellular carcinoma.