Two found no difference in risk for antenatal depression between women managing their GDM with or without insulin (references 15 and 16 in Appendix S2), whereas another study did find an increased risk for postnatal depression in women using insulin (reference 45 in Appendix S2) but another study in the postpartum did not (reference 47 in Appendix S2). The gene discussed is INS; the disease is gestational diabetes.