First, we employed a heterozygous Scn1a+/− mouse model lacking one copy of the NaV1.1 protein (Thiele et al., 2018) that is used as a model for a variety of seizure types from simple febrile seizures to severe genetic disorders such as Dravet (Nakayama et al., 2018) and Lennox–Gastaut syndromes (Zhou et al., 2018). Here, SCN1A is linked to hereditary disease.