APOE and atherosclerosis: To address the contribution of mTrib1 in early atherosclerosis, we first transplanted bone marrow cells from the Trib1mKO and Trib1mTg mice and their respective controls (i.e., non-CRE, floxed KO, and Tg alleles) into 12- to 13-week-old lethally irradiated male ApoE−/− mice (Fig. 2A).