VWF and vascular neoplasm: Factor VIII-related antigen often lacks immunoreactivty in vascular tumors [10] Folpe et al. [19], reported that the FLI-1 was expressed by 50 vascular tumours (94%) out of 53, including 20 case of angiosarcomas among 22: this study highlighted the interesting role of the FLI-1 as new nuclear marker of vascular tumors.