In addition, recruitment of monocytes during lung infection is critical for bacterial clearance.27 Clinically, reduction of HLA‐DR expression in monocytes is a prognostic marker of stroke‐induced immune suppression and SAP.2, 28, 29 Interestingly, we found that ischemic stroke increases the expression of the monocyte chemoattractant CCL2 in the lungs, yet monocyte infiltration into the lungs was not observed. This evidence concerns the gene CCL2 and stroke disorder.