Accumulating evidence demonstrated that MYST1 was correlated with the progression of various cancer cell types including medulloblastoma, breast cancer, ovarian cancer, colorectal carcinoma, gastric cancer, renal cell carcinoma, and NSCLC.17, 18, 19, 20, 21 Here we described the functional significance of MYST1 expression in GBM. This evidence concerns the gene KAT8 and hereditary clear cell renal cell carcinoma.