Many studies also showed that MYST1/MOF played pivotal roles in responding to DNA damage.16, 57, 58 In addition, It was reported that EGFR‐AKT/ERK signaling pathway was a major regulator of G2M phase in GBM.59 Downregulated EGFR‐AKT/ERK signaling pathway by MYST1 silencing might also be a reason for G2/M phase arrest. This evidence concerns the gene EGFR and glioblastoma.