The Lnc‐SNHG family includes many members, in which the most associated with digestive cancers are SNHG1, GAS (SNHG2), SNHG3, SNHG5, SNHG6, SNHG7, SNHG8, SNHG9, SNHG12, DANCR (SNHG13), SNHG14, SNHG15, SNHG16, SNHG17, SNHG18 and SNHG20. Multiple molecular regulatory mechanisms of each SNHG member are involved in different human cancers. This evidence concerns the gene SNHG16 and cancer.