The phosphatidylinositol 3‐kinase‐AKT signaling pathway might affect this drug resistance.111 Cui et al suggested that SNHG1 could upregulate the key markers of the NOTCH signaling pathway to affect pancreatic cancer proliferation and invasion.112 Additionally, SNHG1 also played a crucial role in pancreatic ductal adenocarcinoma. This evidence concerns the gene SNHG1 and pancreatic neoplasm.