Bai J et al and Tian T et al showed that SNHG1 was mainly located in the cytoplasm.40, 41SNHG1 could sponge MIR‐497/MIR‐195‐5p to influence EMT to facilitate cancer cell migration and invasion,40 and sponge MIR‐145 to increase the expression of MIR‐145’s targets, to promote colorectal cancer cell proliferation.41 On the contrary, Xu et al confirmed the presence of SNHG1 mainly in the nucleus by performing in situ hybridization and nuclear slurry separation experiments. This evidence concerns the gene MIR145 and colorectal cancer.