The phosphatidylinositol 3‐kinase‐AKT signaling pathway might affect this drug resistance.111 Cui et al suggested that SNHG1 could upregulate the key markers of the NOTCH signaling pathway to affect pancreatic cancer proliferation and invasion.112 Additionally, SNHG1 also played a crucial role in pancreatic ductal adenocarcinoma. The gene discussed is SNHG1; the disease is familial pancreatic carcinoma.