Neutrophils isolated from patients with G6PC3 or G6PT deficiency, show concentrations of 1,5‐anhydroglucitol‐6‐phosphate (≈ 3 mM) that are far above the Ki of hexokinase 3 (the main hexokinase in neutrophils)34 for this inhibitor, and close to 1000‐fold higher than the concentration found in neutrophils from healthy controls.26 This evidence concerns the gene G6PC1 and hyperinsulinemic hypoglycemia, familial, 4.