In addition, two subtypes of neutrophils have been reported at least in murine tumor models: TGFβ-independent type 1 (N1) with antimicrobial functions, and TGFβ-dependent tumor-associated neutrophils (N2, TANs) possessing pro-tumor and proangiogenic functions [263, 264]. The gene discussed is TGFB1; the disease is neoplasm.