LINC02525 and neuroblastoma: Clonogenic assays showed that treatment with doxycycline did not have an effect on colony formation in doxycycline-inducible control shRNA cells, but almost completely abolished and indeed completely abolished clonogenic capacity of doxycycline-inducible lncNB1 shRNA-1 and lncNB1 shRNA-2 BE(2)-C and Kelly cells, respectively (Fig. 7a, b), suggesting that lncNB1 plays a critical role in neuroblastoma tumorigenesis.