CD81 and infection: Peptides used in the current study have been recently shown to contain amino acid residues involved in CD81 blockade such as L413, G418, W420, G523, P525, Y527, W529 and G530 [55] Moreover, rabbits immunized with HVR1 derived peptides generated cross- reactive antibodies to HCV at high titers that blocked MOLT-4 infection with HCV [56].