The miRNA-mRNA network shows that significantly deregulated miRNAs in the FS and FSO groups target genes involved in the MG development (red circles) (Figure 3) and/or associated with breast cancer (blue circles), including Egfr, Igf-1, Igf-1R, Hif1a, Ets1, and pgr. The gene discussed is IGF1; the disease is breast carcinoma.