Mohebbati et al. have come to the facts by researching the data banks for curcumin as an inhibitor of the tumor necrosis factor production (TNF-α) and prostaglandin E2 (PGE2), but it increases the caspase activity (3, 8 i 9) in HL-60 prostate carcinoma. The gene discussed is TNF; the disease is prostate carcinoma.