FOXA2 might act as a suppressor of tumor metastasis via regulation of epithelial to mesenchymal transition or tumor-related signaling pathways [15, 16] Low FoxA2 expression was found to be positively correlated with higher tumor stage (p=0.032), which indicates the negative relationship between FOXA2 expression and advanced tumor stage. This evidence concerns the gene FOXA2 and neoplasm.