CDH2 and acute myeloid leukemia: Again, this finding is associated with increased expression of N‐cadherin in the 3D model.93 A 3D polyurethane model to study AML has been established by Blanco and colleagues.94 This model has been used to study the effects of physiologic levels of oxidative and glucose stress of AML and has shown that cells grown in 3D are better able to adapt to oxidative stress than those cells grown in a 2D model.