GIP and Hyperglycemia: The anti‐incretin dopamine is able to inhibit glucose‐stimulated insulin secretion in pancreatic β‐cells by antagonizing GIP‐stimulated cAMP increases,26 and there is evidence that gut‐produced dopamine is responsible at least in part for the recovery from hyperglycemia seen in patients that have undergone bariatric surgery.24 However, this is the first study to our knowledge that shows in a diabetic mouse model that serum levels of dopamine are significantly increased compared to nondiabetic control animals.