Amisulpride has also been shown to restore insulin secretion and lower blood glucose levels in diabetic mice,32 and deregulation of glucose homeostasis is a common feature in patients taking antipsychotics.68 Modest antidiabetic effects of amisulpride have been reported.69 We considered the possibility that recovery of a normal bone phenotype in our diabetic mice was simply due to a recovery of insulin secretion and reversal of hyperglycemia. The gene discussed is INS; the disease is Hyperglycemia.