INS and type 2 diabetes mellitus: However, the MAGE (Ln(MAGE): 1.79 ± 0.50 (H) vs. 1.60 ± 0.35 (L), p = 0.032; 1.79 ± 0.50 (H) vs. 1.36 ± 0.37 (C), p < 0.001; and 1.60 ± 0.35 (L) vs. 1.36 ± 0.37 (C), p < 0.001, respectively) showed a significantly progressive increase alongside IA titer in T2DM patients with insulin therapy.