The aim of this study was to investigate the influence of the two growth factors; Granulocyte-Colony Stimulating Factor (G-CSF, Lenograstim), and recombinant human Granulocyte-Macrophage Colony Stimulating Factor, (rHu GM-CSF, Molgramostim, Mielogen)], as possible therapeutic agents in experimental colitis in rats. Here, CSF2 is linked to colitis.