NFE2L2 and viral infectious disease: Virus infection at 24 hpi significantly decreased the acetylation levels of the nucleus Nrf2 protein, which was reduced to ~60.7% relative to that in the mock-infected control (Figure 6(c)), which is in consistent with our findings that virus infection inhibited the accumulation of Nrf2 in the nucleus (Figure 5), and depressed the expression of HO-1 and NQO1 (Figures 1(c), 1(d), and 1(f)).