The plasma levels of IFN-γ, IL-6 and IL-10 were higher in HAT (72.23, 55.04 and 115.5 pg/ml) or malaria cases (14.72, 10.74, and 11.44 pg/ml) respectively than healthy controls (8.612, 3.513, and 3.812 pg/ml) (HAT significance: P < 0.0001, P < 0.0001, P < 0.0001 or malaria significance: P = 0.0169, P = 0.0015, and P = 0.0288) respectively. The gene discussed is IFNG; the disease is malaria.