IL37 and myocardial infarction: Many papers have reported that IL-37 transgenic mice exhibit less severe inflammation in models of myocardial infarction, endotoxin shock, colitis, lung, and spinal cord injury, while dendritic cells (DCs) from IL-37tg mice exhibit characteristics of tolerogenic DCs, and these mice have reduced antigen-specific responses [8, 12, 26].