CD8A and neoplasm: To further infer precursor frequency, we sequenced TRB-CDR3 from flow-sorted CD8+ T-cells purified from available donor leukapheresis products (HD_A, HD_B, and KCD_D) as well as two additional PBMC samples and a tumor-infiltrating lymphocyte sample also from donor KCD_D (Supplementary Table 1 and Supplementary Fig. 1).