Meanwhile, another study proved that ligand-dependent EphA7 but not the truncated secreted form of EphA7 induced prostate cancer cell apoptosis; and tyrosine 791 phosphorylation of EphA7, which is required in prostate cancer cell apoptosis, is dependent on the stimulation of ephrinA5 ligand [42]. The gene discussed is EPHA7; the disease is Familial prostate cancer.