Consistently, the statistical analysis of TPM (transcripts per million) data obtained from TCGA database [25], consisting of 497 prostate tumor tissues and 52 normal tissues, showed that DEPTOR expression at the mRNA level was also significantly decreased in prostate cancer tissues, compared with that of normal tissue (p < 0.001) (Fig. 1c). The gene discussed is DEPTOR; the disease is Familial prostate cancer.