Immunohistochemical examination of 10 distinct tumors showed that in most of the tumors, Tomato+ tumor cells express melanocytic markers Dct and MITF, neuronal markers Nestin, Tubb3 and Gfap, mesenchymal marker Pdgfra and proliferation marker Ki67 (Supplementary Fig. 12d). This evidence concerns the gene DCT and neoplasm.