Clinically, data from two cohorts of PCa obtained from Oncomine database (Vanaja Prostate dataset [203065_s_at]28 and Lapointe Prostate dataset [290525]29) indicated that Cav-1 mRNA expression was significantly higher in metastasis specimens compared with the primary tumor specimens (Fig. 1e). The gene discussed is CAV1; the disease is posterior cortical atrophy.