CAV1 and posterior cortical atrophy: Indeed, the presence of Cav-1 was detected in PCa TDEs; we further quantified the amount of Cav-1 in TDE; an ~ 20–30 ng Cav-1 protein was detected from TDE of LNCaP or Du145 respectively (Fig. 4d) based on the standard curve (Supplemental S3A).