To investigate the role of the GATA3 and UTX in breast cancer metastasis in vivo, MDA-MB-231 cells that stably express firefly luciferase (MDA-MB-231-Luc-D3H2LN, Xenogen) were co-infected with lentiviruses carrying empty vector + shSCR, GATA3 + shSCR, or GATA3 + shUTX. Here, KDM6A is linked to breast carcinoma.