Differences in the expression of tumor markers between the pTACE and CA4P + pTACE groups as indicated by immunohistochemical staining were as follows: Ki67, 0.75 ± 0.67% vs 0.42 ± 0.42%; CD31 (MVD),10.6 ± 4.16% vs 8.40 ± 4.01%; VEGF, 148.63 ± 42.48% vs 129.76 ± 36.03%, respectively. This evidence concerns the gene MKI67 and neoplasm.