Sorafenib is an oral small molecule multikinase inhibitor that exerts an anticancer effect by simultaneously suppressing angiogenesis via inhibition of vascular endothelial growth factor receptor (VEGFR-1,2,3) and platelet-derived growth factor receptor (PDGFR) and the growth of tumor cells directly through downregulation of the Ras/Raf/Mek/Erk signaling pathway [6, 7]. The gene discussed is FLT1; the disease is neoplasm.