The reduced migration and invasion of cancer cells upon RNA interference (RNAi)-mediated knockdown of AXL or blockade of AXL signalling were also reported in liposarcoma, pancreatic cancer, lung adenocarcinoma, breast cancer and thyroid cancer [69, 76, 85–87], thus demonstrating the role of AXL signalling as a good target for conferred migratory and invasive properties. This evidence concerns the gene AXL and familial pancreatic carcinoma.