PLAT and Stroke: Those included care in a specialised stroke unit (SU), [14], thrombolytic therapy through tissue plasminogen activator (t-PA) for acute ischemic stroke (within 4.5 h of initial onset) [15, 16], aspirin therapy for acute ischaemic stroke (within 48 h) [17], and decompressive surgery (within 48 h) [18] to reduce stroke-related mortality and morbidity [19].