The laboratory values revealed significant hyponatremia (120 mmol/L), hypochloremia (88 mmol/L, normal 99–110 mmol/L), compensatory metabolic acidosis (pH 7.36, BB − 3.4 mmol/L), elevated AST (75 IU/L, normal 13–35 IU/L), a low serum cortisol of 1.9 μg/dL (normal 3.7–19.4 μg/dL), and a high serum ACTH of 313 ng/L (normal 7.2–63.3 ng/L). This evidence concerns the gene POMC and Hyponatremia.