KLK3 and posterior cortical atrophy: vs. 69.7 yrs., p = 0.09), a lower PSA level (11.5 ng/ml vs. 13.0 ng/ml, p = 0.07), a larger prostate volume (72.1 ml vs. 53.6 ml, p = 0.045) and a much lower PCa detection rate (10.6% vs. 70.9%, p<0.001) compared with the combination cohort (PI-RADS 3–5).