Finally, the analysis of paired patients’ blood samples (for, respectively, four and seven patients for RA and PsA) before and under MTX treatment showed significantly increased CD73 levels on Th1 and Th1.17 subsets (Figure 3D), the two populations with significantly altered CD73 expression in untreated patients compared to HD (Figure 1E). Here, NT5E is linked to rheumatoid arthritis.