CBFB and neoplasm: The swift expansion of the tumor population and rapid impairment of normal hematopoiesis led to a decreased time of survival in Cbfb+/56MFbxo9+/− and Cbfb+/56MFbxo9−/− transplant cohorts, compared to Cbfb+/56MFbxo9+/+ (Figure 5C).